姓名:顾相伶 性别:男
出生年月:1974.08 籍贯:山东宁阳
职称:教授 职务:副院长
毕业院校:山东大学 学位:博士
联系电话:0534-8985576 E-mail:guxiangling2004@163.com
通信地址:德州市大学西路566号members48365365(邮编:253023)
研究方向:
功能高分子&纳米材料
研究兴趣
近年来从事功能高分子材料、生物医用高分子相关研究,涉及高分子基纳米复合材料、刺激响应性多孔水凝胶、水分散体系天然高分子药用微胶囊、功能化聚合物微球的制备及组装、新型药用辅料的合成、矿用防水、充填、灭火材料及静态爆破材料的研制以及聚氨酯材料的应用开发等。
科研课题
1.山东省重点研发计划项目:高取代、高粘度羟丙基甲基纤维素药用辅料的关键生产工艺研究,2015/01-2017/12,主持,结题。
2.山东省自然科学基金项目:磁靶向pH敏感高效转基因载体的构建及其转染性能研究,2011/01-2013/12,主持,结题。
3.山东省教育规划课题:基于PBL法的医学化学教学模式研究,2012/01-2013/12,主持,结题。
4.国家自然科学基金面上项目:新仿生修饰和功能化的超顺磁性Fe3O4纳米粒子MRI造影剂及其安全性评价, 2013/01-2016/12, 第二位,结题。
学术论文
1. Xiangling Gu*, Meng Yuan, Yaolin Liu, Haiyan Liu, Jiwei Wu, ChunHui Li. Review On SPG Membrane Emulsification: An Efficient Approach to Prepare Uniform Microspheric Drug Carrier, MOJ Drug Design Development & Therapy, 2018.06 (Accepted)
2. Xiangling Gu*, Yaolin Liu, Jiwei Wu, Kaiwen Zhou, Haiyan Liu, ChunHui Li*. Observation On Current Situation Of Higher Pharmaceutical Education In China From A New Perspective. International Conference on Medicine Sciences and Bioengineering (ICMSB 2018) June 22-24, Suzhou, China
3. Xiangling Gu, Xinfeng Song, Yancong Zhang, Hanwen Sun, Xiang Zheng Kong, Chunhua Fu, Shuqin Cui, Zhiqin Zhang. A green approach to crosslinked polymer microspheres with undoped methacrylate monomers and their potential application as dental restorative materials, RSC Advances, 2015, 5:25840-25848
4. Xiangling Gu, Hanwen Sun, Xiang Zheng Kong, Chunhua Fu, Hui Yu, Jing Li, Jinghe Wang. A green protocol to prepare monodisperse poly (TMPTMA–styrene) microspheres by photoinitiated precipitation polymerization in low-toxicity solvent, Colloid and Polymer Science, 2013, 291:1771-1779。
5. Xiangling Gu, Xiaoli Zhu, Xiang Zheng Kong, Zhao Zhang. One step in situ self-assembly of microspheres through precipitation polymerization in the presence of an organic template, Soft Matter, 2011, 7:4055-4061.
6. Xiangling Gu, Xiaoli Zhu, Xiang Zheng Kong, Yebang Tan. Comparisons of simple and complex coacervations for preparation of sprayable insect sex pheromone microcapsules and release control of the encapsulated pheromone molecule, Journal of Microencapsulation, 2010, 27(4):355-364。
7. Xiangling Gu, Yancong Zhang, Hanwen Sun, Xinfeng Song, Chunhua Fu, Pingxuan Dong. Mussel-Inspired Polydopamine Coated Iron Oxide Nanoparticles for Biomedical Application, Journal of Nanomaterials, 2015, Article ID:154592
8. Xiangling Gu, Xinfeng Song, Maojiang Dong, et al. Implementation of Total Quality Management in Higher Pharmaceutical Education: Opportunity and Challenge. Indian Journal of Pharmaceutical Education and Research, 2016, 50(1):34-38.
9. Xiangling Gu, Xinfeng Song, Hanwen Sun, et al. Teaching Reform of Pharmaceutical Chemistry with PBL Method. Indian Journal of Pharmaceutical Education and Research, 2016, 50(4):530-533.
10. Xinfeng Song, Xiangling Gu, Hanwen Sun, Chunhua Fu, Yancong Zhang, Pingxuan Dong. Biomemetic Modification and In Vivo Safety Assessment of Superparamagnetic Iron Oxide Nanoparticles, Journal for Nanoscience and Nanotechnology, 2016,16(4):4100-4107.
11. Xiaoli Zhu, Xiangling Gu, Lina Zhang, Xiang Zheng Kong. Preparation and characterization of nanosized P(NIPAM-MBA) hydrogel particles and adsorption of bovine serum albumin on their surface, Nanoscale Research Letters, 2012, 7:519-527。
12. Xiang Zheng Kong, Xiangling Gu, Xiaoli Zhu, Zhiguo Zhang. Spreadable dispersion of insect sex pheromone capsules, preparation via complex coacervation and release control of the encapsulated pheromone component molecule. Biomedical microdevice. 2009, 11(1):275-285。
13. Xiang Zheng Kong, Xiangling Gu, Xiaoli Zhu, Lina Zhang. Precipitation polymerization in ethanol and ethanol/water to prepare uniform microspheres of poly(TMPTA-styrene). Macromolecular Rapid Communications. 2009, 30 (11):909-914。
14. Xiangling Gu, Jie Lian, Xiaoli Zhu, Weipeng Liu, and Xiang Zheng Kong. Encapsulation of dodecanol, an insect pheromone component, by coacervation of acacia gum and gelatin and its release therefrom. Polymer Materials: Science and Engineering, 2007, 97:914-915。
15. Lina Liu, Xiangling Gu, Xiaoli Zhu, Zhiguo Zhang, Xiang Zheng Kong. Encapsulation of insect sex pheromone via simple and complex coacervation of gelatin. Amino Acids, 2009, 37 (1): 97
16. Shuqin Cui, Hanwen Sun, Xiangling Gu, E Lv, Yancong Zhang, Pingxuan Dong, Chunhua Fu, Chao Zhu. Gene expression profiling analysis of locus coeruleus in idiopathic Parkinson’s disease by bioinformatics, Neurological Sciences, 2015, 36(1):97-102。
17. Hanwen Sun, Xinjun Zhu, Lianying Zhang, Xiangling Gu, Jinghe Wang, Jing Li, Yancong Zhang, PDEA-coated Magnetic Nanoparticles for Gene Delivery to Hep G2 Cells, Biotechnology and Bioprocess Engineering, 2013, 18: 648-654。
18. Yancong Zhang, Lianying Zhang, Xinfeng Song, Xiangling Gu, Hanwen Sun, Chunhua Fu, Fanzong Meng. Synthesis of superparamagnetic iron oxide nanoparticles modified with MPEG-PEI via photochemistry as new MRI contrast agent, Journal of Nanomaterials, 2015, Article ID 417389
19. Jiwei Wu, Xinfeng Song, Hanwen Sun,Yancong Zhang, Xiangling Gu, Pingxuan Dong, Shuqin Cui, Chunhua Fu. Chitosan nano carriers loading anti-tumor drugs. Journal for Nanoscience and Nanotechnology, 2015, 32:113-127。
20. 顾相伶, 朱晓丽, 张志国, 谭业邦, 孔祥正, 刘维鹏. 复凝聚法制备昆虫激素模拟物十二醇微胶囊及其释放性能研究.高等学校化学学报. 2008, 29 (6): 1247-1254 。
21. 顾相伶, 朱晓丽, 张利娜, 孔祥正, 谭业邦, 鲁毅. 低毒性新溶剂体系乙醇或乙醇-水中沉淀聚合制备单分散聚合物微球. 化学学报, 2009, 67(21): 2486-2494
22 张召, 顾相伶, 朱晓丽, 孔祥正, 沉淀聚合制备聚(季戊四醇三丙烯酸酯—苯乙烯)单分散微球及其形成机理. 物理化学学报, 2012, (04):892-896。
23. 朱晓丽, 顾相伶, 廉洁, 张志国, 孔祥正. 昆虫激素模拟化合物十二醇微胶囊的制备与释放行为研究. 化学学报, 2008, 66(1):121-128.
24. 朱晓丽, 顾相伶, 张志国, 孔祥正. 单/复凝聚法昆虫激素微胶囊的制备与释放行为研究.高分子学报. 2007, (5):491-496.
25. 姜文巧, 张利娜, 顾相伶, 朱晓丽, 孔祥正. 三羟甲基丙烷三丙烯酸酯-苯乙烯沉淀聚合高产率制备高交联单分散聚合物微球, 高分子学报, 2013, (03):406-413。
26. 朱晓丽, 刘维鹏, 顾相伶, 孔祥正. 大豆分离蛋白-十二烷基硫酸钠微胶囊的制备与表征. 化学学报,2009 (13):1497—1502
27. 孔祥正, 廉洁, 朱晓丽, 顾相伶, 张志国. 聚[2-(甲基丙烯酰氧)乙基三甲基氯化铵]/阿拉伯胶复凝聚法十二醇微胶囊的制备. 高分子学报. 2008, (8)797-804.
28. 龙云霄, 于锦锦, 袁梦, 刘耀林, 顾相伶*. 高取代、高粘度羟丙基甲基纤维素药用辅料的制备与应用, 中国药学会2017年制药工程专业委员会学术年会论文集, 2017.10.21-22, 合肥.
申请专利
1. 顾相伶, 刘耀林, 梁欣.一种羟丙基甲基纤维素羟丙基取代度的测试方法.2016.10.01中国发明专利,CN201610875067.9。(公开)
2. 顾相伶 ,孙汉文 ,刘耀林 ,宋新峰 ,华玉山. 一种羟丙基甲基纤维素甲基取代度的测试方法2015.08.20,中国发明专利, CN201510501971.9。(公开)
3. 顾相伶 ,刘耀林 ,袁梦 ,孙汉文 ,宋新峰 ,崔淑芹 .一种羟丙基甲基纤维素纳米微球的制备方法,2015.08.20,中国发明专利,CN201510515297.X。(公开)
4. 孙汉文, 顾相伶, 于国雷, 李瑞林, 李万平. 光引发沉淀聚合制备单分散高分子微球的方法, 2013.8.28, 中国发明专利, CN201310200828.7。 (公开)
5. 孙汉文, 顾相伶, 付春华, 张成良, 王凯. 适于密闭体系光化学聚合的反应装置, 2012.12.5, 实用新型专利, CN201220194779.1。 (授权)
6. 孔祥正, 顾相伶, 朱晓丽, 张志国, 廉洁. 一种环境友好型可控缓释灭虫剂及其制备方法, 2008.4.16, 中国发明专利, CN101161068。 (授权)
7. 崔淑芹, 孙汉文, 顾相伶, 付春华, 董平轩. 帕金森病震颤记录仪, 2013.08.08, 实用新型专利, CN203388861U。 (授权)
8. 张海涛, 顾相伶, 郑梅, 于国雷, 张峰, 崔海波, 王伟峰. 矿用静态碎裂剂及使用方法. 2013.7.31, 中国发明专利, CN103224349A。(授权)
9. 张海涛, 顾相伶, 于国雷, 郑梅, 崔海波, 张峰, 王伟峰. 煤矿用封孔剂及制备使用方法. 2013.7.31, 中国发明专利, CN103224377A。(授权)
